PPP1R8 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2712333

Product Details

Target: PPP1R8 (Protein Phosphatase 1, Regulatory Subunit 8 (PPP1R8))

Protein Type: Recombinant

Protein Characteristics: Transcript Variant 2

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This PPP1R8 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human NIPP-1 (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: PPP1R8 (Protein Phosphatase 1, Regulatory Subunit 8 (PPP1R8))

Alternative Name: Nipp-1 (PPP1R8 Products)

Synonyms: ARD-1 Protein, ARD1 Protein, NIPP-1 Protein, NIPP1 Protein, PRO2047 Protein, 6330548N22Rik Protein, AU044684 Protein, PPP1R8 Protein, ard-1 Protein, ard1 Protein, nipp-1 Protein, nipp1 Protein, ppp1r8 Protein, si:ch211-206a7.1 Protein, protein phosphatase 1 regulatory subunit 8 Protein, protein phosphatase 1, regulatory subunit 8 Protein, protein phosphatase 1, regulatory (inhibitor) subunit 8 Protein, protein phosphatase 1, regulatory subunit 8b Protein, protein phosphatase 1 regulatory subunit 8 L homeolog Protein, protein phosphatase 1, regulatory subunit 8a Protein, protein phosphatase 1 regulatory subunit 8 S homeolog Protein, PPP1R8 Protein, Ppp1r8 Protein, ppp1r8b Protein, ppp1r8.L Protein, ppp1r8a Protein, ppp1r8.S Protein

Background: This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA.

Molecular Weight: 22.5 kDa

NCBI Accession: NP_612568