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CTPS2 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

CTPS2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2712617
  • Target See all CTPS2 Proteins
    CTPS2 (CTP Synthase II (CTPS2))
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 2
    Origin
    • 4
    • 1
    • 1
    Human
    Source
    • 2
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This CTPS2 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human CTP synthase 2 (transcript variant 2) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product CTPS2 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    CTPS2 (CTP Synthase II (CTPS2))
    Alternative Name
    Ctp Synthase 2 (CTPS2 Products)
    Synonyms
    A830031M15Rik Protein, AI326475 Protein, Ctpsh Protein, CTP synthase 2 L homeolog Protein, CTP synthase 2 Protein, cytidine 5'-triphosphate synthase 2 Protein, ctps2.L Protein, CTPS2 Protein, ctps2 Protein, Ctps2 Protein
    Background
    The protein encoded by this gene catalyzes the formation of CTP from UTP with the concomitant deamination of glutamine to glutamate. This protein is the rate-limiting enzyme in the synthesis of cytosine nucleotides, which play an important role in various metabolic processes and provide the precursors necessary for the synthesis of RNA and DNA. Cancer cells that exhibit increased cell proliferation also exhibit an increased activity of this encoded protein. Thus, this protein is an attractive target for selective chemotherapy. Alternative splicing results in multiple transcript variants.
    Molecular Weight
    65.5 kDa
    NCBI Accession
    NP_787055
    Pathways
    Ribonucleoside Biosynthetic Process
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