CYLD Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
(1 reference)-
- Target See all CYLD Proteins
- CYLD (Cylindromatosis (Turban Tumor Syndrome) (CYLD))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 2
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CYLD protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human CYLD (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product CYLD Protein
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Cylindromatosis (Turban Tumor Syndrome) (CYLD) (AA 1-226) protein (His-IF2DI Tag)
CYLD Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Cylindromatosis (Turban Tumor Syndrome) (CYLD) (AA 854-953) protein (GST tag)CYLD Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Cylindromatosis (Turban Tumor Syndrome) (CYLD) (AA 1-956) protein (Strep Tag)Crystallography grade CYLD Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Cylindromatosis (Turban Tumor Syndrome) (CYLD) (AA 1-952) protein (Strep Tag)Crystallography grade CYLD Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Cylindromatosis (Turban Tumor Syndrome) (CYLD) (Transcript Variant 3) protein (Myc-DYKDDDDK Tag)CYLD Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Cylindromatosis (Turban Tumor Syndrome) (CYLD) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)CYLD Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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: "CaMKII mediates recruitment and activation of the deubiquitinase CYLD at the postsynaptic density." in: PLoS ONE, Vol. 9, Issue 3, pp. e91312, (2014) (PubMed).
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: "CaMKII mediates recruitment and activation of the deubiquitinase CYLD at the postsynaptic density." in: PLoS ONE, Vol. 9, Issue 3, pp. e91312, (2014) (PubMed).
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- Target
- CYLD (Cylindromatosis (Turban Tumor Syndrome) (CYLD))
- Alternative Name
- Cyld (CYLD Products)
- Synonyms
- BRSS Protein, CDMT Protein, CYLD1 Protein, CYLDI Protein, EAC Protein, MFT Protein, MFT1 Protein, SBS Protein, TEM Protein, USPL2 Protein, 2010013M14Rik Protein, 2900009M21Rik Protein, C130039D01Rik Protein, mKIAA0849 Protein, cyld Protein, LRRGT00003 Protein, Rp1 Protein, Rp1h Protein, CYLD lysine 63 deubiquitinase Protein, cylindromatosis (turban tumor syndrome), a Protein, CYLD Protein, Cyld Protein, cylda Protein
- Background
- This gene is encodes a cytoplasmic protein with three cytoskeletal-associated protein-glycine-conserved (CAP-GLY) domains that functions as a deubiquitinating enzyme. Mutations in this gene have been associated with cylindromatosis, multiple familial trichoepithelioma, and Brooke-Spiegler syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
- Molecular Weight
- 106.9 kDa
- NCBI Accession
- NP_001035814
- Pathways
- Apoptosis, Activation of Innate immune Response
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