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Claudin 19 Protein (CLDN19) (Transcript Variant 1) (Myc-DYKDDDDK Tag)

CLDN19 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2712853
  • Target See all Claudin 19 (CLDN19) Proteins
    Claudin 19 (CLDN19)
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 1
    Origin
    • 4
    • 1
    Human
    Source
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This Claudin 19 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human Claudin-19 / CLDN19 (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product CLDN19 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    Claudin 19 (CLDN19)
    Alternative Name
    Claudin-19,cldn19 (CLDN19 Products)
    Synonyms
    HOMG5 Protein, claudin-19 Protein, zgc:112141 Protein, claudin 19 Protein, claudin 19 S homeolog Protein, CLDN19 Protein, Cldn19 Protein, cldn19.S Protein, cldn19 Protein
    Background
    The product of this gene belongs to the claudin family. It plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Defects in this gene are the cause of hypomagnesemia renal with ocular involvement (HOMGO). HOMGO is a progressive renal disease characterized by primary renal magnesium wasting with hypomagnesemia, hypercalciuria and nephrocalcinosis associated with severe ocular abnormalities such as bilateral chorioretinal scars, macular colobomata, significant myopia and nystagmus. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.
    Molecular Weight
    23 kDa
    NCBI Accession
    NP_683763
    Pathways
    Cell-Cell Junction Organization, Hepatitis C
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