CNOT7 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2712912

Product Details

Target: CNOT7 (CCR4-NOT Transcription Complex, Subunit 7 (CNOT7))

Protein Type: Recombinant

Protein Characteristics: Transcript Variant 1

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This CNOT7 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human CNOT7 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: CNOT7 (CCR4-NOT Transcription Complex, Subunit 7 (CNOT7))

Alternative Name: Cnot7 (CNOT7 Products)

Synonyms: CNOT7 Protein, CAF1 Protein, fd59c07 Protein, fj07d05 Protein, wu:fd59c07 Protein, wu:fj07d05 Protein, zgc:153168 Protein, caf1 Protein, Caf1a Protein, hCAF-1 Protein, AU022737 Protein, CAF-1 Protein, Caf1 Protein, Pop2 Protein, CCR4-NOT transcription complex subunit 7 Protein, ccr4-not transcription complex, subunit 7 Protein, CCR4-NOT transcription complex, subunit 7 Protein, ccr4-not transcription complex, subunit 7, putative Protein, CCR4-NOT transcription complex subunit 7 S homeolog Protein, CNOT7 Protein, CNL04550 Protein, GL50803_10606 Protein, GL50803_8209 Protein, CGB_D2510C Protein, cnot7 Protein, cnot7.S Protein, Cnot7 Protein

Background: The protein encoded by this gene binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The encoded protein downregulates the innate immune response and therefore provides a therapeutic target for enhancing its antimicrobial activity against foreign agents. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and X.

Molecular Weight: 32.6 kDa

NCBI Accession: NP_037486

Pathways: Ribonucleoprotein Complex Subunit Organization