Factor XI Protein (Myc-DYKDDDDK Tag)
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- Target See all Factor XI (F11) Proteins
- Factor XI (F11) (Coagulation Factor XI (F11))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Factor XI protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Coagulation factor XI (F11) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product F11 Protein
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Coagulation Factor XI (F11) (AA 19-625) protein (His tag)
F11 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Coagulation Factor XI (F11) (AA 1-625) protein (GST tag)F11 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Coagulation Factor XI (F11) (AA 286-385) protein (GST tag)F11 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Coagulation Factor XI (F11) (AA 19-387) protein (His tag)Crystallography grade F11 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Coagulation Factor XI (F11) (AA 388-625) protein (His tag)Crystallography grade F11 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Coagulation Factor XI (F11) (AA 19-389) protein (His tag)Crystallography grade F11 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Coagulation Factor XI (F11) (AA 390-624) protein (His tag)Crystallography grade F11 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- Factor XI (F11) (Coagulation Factor XI (F11))
- Abstract
- F11 Products
- Synonyms
- FXI Protein, 1600027G01Rik Protein, AI503996 Protein, Cf11 Protein, LRRGT00086 Protein, coagulation factor XI Protein, F11 Protein, CpipJ_CPIJ000593 Protein, CpipJ_CPIJ001060 Protein, CpipJ_CPIJ002752 Protein, CpipJ_CPIJ003631 Protein, CpipJ_CPIJ004041 Protein, CpipJ_CPIJ004093 Protein
- Background
- This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality.
- Molecular Weight
- 69.9 kDa
- NCBI Accession
- NP_000119
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