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CABLES1 Protein (His tag)

CABLES1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2713000
  • Target See all CABLES1 Proteins
    CABLES1 (Cdk5 and Abl Enzyme Substrate 1 (CABLES1))
    Protein Type
    Recombinant
    Origin
    • 2
    • 1
    Human
    Source
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This CABLES1 protein is labelled with His tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human CABLES1 (full length, N-term HIS tag, transcript variant 1) protein expressed in E.coli.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product CABLES1 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the N-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    CABLES1 (Cdk5 and Abl Enzyme Substrate 1 (CABLES1))
    Alternative Name
    Cables1 (CABLES1 Products)
    Synonyms
    CABLES1 Protein, si:dkey-2p18.3 Protein, CABL1 Protein, CABLES Protein, HsT2563 Protein, IK3-1 Protein, Cables Protein, ik3-1 Protein, Cdk5 and Abl enzyme substrate 1 Protein, CDK5 and Abl enzyme substrate 1 Protein, CABLES1 Protein, cables1 Protein, CpipJ_CPIJ019832 Protein, Cables1 Protein
    Background
    This gene encodes a protein involved in regulation of the cell cycle through interactions with several cyclin-dependent kinases. One study (PMID: 16177568) reported aberrant splicing of transcripts from this gene which results in removal of the cyclin binding domain only in human cancer cells, and reduction in gene expression was shown in colorectal cancers (PMID: 17982127).Multiple transcript variants encoding different isoforms have been found for this gene.
    Molecular Weight
    41.7 kDa
    NCBI Accession
    NP_612384
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