CPN1 Protein (His tag)

Catalog No. ABIN2713157

Product Details

Target: CPN1 (Carboxypeptidase N Subunit 1 (CPN1))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This CPN1 protein is labelled with His tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human Carboxypeptidase N catalytic chain (full length, N-term HIS tag) protein expressed in E.coli.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the N-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: CPN1 (Carboxypeptidase N Subunit 1 (CPN1))

Alternative Name: Carboxypeptidase N Catalytic Chain (CPN1 Products)

Synonyms: CPN Protein, SCPN Protein, Cpn Protein, cb1037 Protein, fa99g08 Protein, wu:fa99g08 Protein, zgc:77485 Protein, cpn Protein, scpn Protein, 0610011F20Rik Protein, carboxypeptidase N subunit 1 Protein, carboxypeptidase N, polypeptide 1 Protein, carboxypeptidase N subunit 1 S homeolog Protein, CPN1 Protein, Cpn1 Protein, cpn1 Protein, cpn1.S Protein

Background: Carboxypeptidase N is a plasma metallo-protease that cleaves basic amino acids from the C terminal of peptides and proteins. The enzyme is important in the regulation of peptides like kinins and anaphylatoxins, and has also been known as kininase-1 and anaphylatoxin inactivator. This enzyme is a tetramer comprised of two identical regulatory subunits and two identical catalytic subunits this gene encodes the catalytic subunit. Mutations in this gene can be associated with angioedema or chronic urticaria resulting from carboxypeptidase N deficiency.

Molecular Weight: 50 kDa

NCBI Accession: NP_001299

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, C21-Steroid Hormone Metabolic Process