CASC3 Protein (Myc-DYKDDDDK Tag)
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- Target See all CASC3 Proteins
- CASC3 (Cancer Susceptibility Candidate 3 (CASC3))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CASC3 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human CASC3 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product CASC3 Protein
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Cancer Susceptibility Candidate 3 (CASC3) (AA 604-703) protein (GST tag)
CASC3 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Cancer Susceptibility Candidate 3 (CASC3) (AA 1-703) protein (Strep Tag)Crystallography grade CASC3 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Cancer Susceptibility Candidate 3 (CASC3) (AA 1-698) protein (Strep Tag)Crystallography grade CASC3 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- CASC3 (Cancer Susceptibility Candidate 3 (CASC3))
- Alternative Name
- Casc3 (CASC3 Products)
- Synonyms
- BTZ Protein, MLN51 Protein, Btz Protein, Mln51 Protein, CASC3 Protein, btz Protein, mln51 Protein, StMLN51 Protein, barentsz Protein, XlMLN51 Protein, cancer susceptibility 3 Protein, cancer susceptibility candidate 3 Protein, protein CASC3 Protein, cancer susceptibility 3 S homeolog Protein, CASC3 Protein, Casc3 Protein, casc3 Protein, casc3.S Protein
- Background
- The product of this gene is a core component of the exon junction complex (EJC), a protein complex that is deposited on spliced mRNAs at exon-exon junctions and functions in nonsense-mediated mRNA decay (NMD). The encoded protein binds RNA and interacts with two other EJC core components. It is predominantly located in the cytoplasm, but shuttles into the nucleus where it localizes to nuclear speckles.
- Molecular Weight
- 76.1 kDa
- NCBI Accession
- NP_031385
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