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CD163 Protein (CD163) (Transcript Variant 1) (Myc-DYKDDDDK Tag)

CD163 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2713450
  • Target See all CD163 Proteins
    CD163
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 1
    Origin
    • 12
    • 7
    • 2
    • 1
    Human
    Source
    • 8
    • 6
    • 4
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This CD163 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human CD163 (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product CD163 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    CD163
    Alternative Name
    CD163 (CD163 Products)
    Synonyms
    DMBT1 Protein, CD163 Protein, CD163v2 Protein, CD163v3 Protein, M130 Protein, MM130 Protein, deleted in malignant brain tumors 1 protein-like Protein, CD163 molecule Protein, CD163 antigen Protein, LOC426820 Protein, CD163 Protein, Cd163 Protein
    Background
    The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
    Molecular Weight
    125.3 kDa
    NCBI Accession
    NP_004235
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