Integrin beta 2 Protein (ITGB2) (Transcript Variant 2) (Myc-DYKDDDDK Tag)
(1 reference)-
- Target See all Integrin beta 2 (ITGB2) Proteins
- Integrin beta 2 (ITGB2)
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 2
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Integrin beta 2 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human CD18 / ITGB2 (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product ITGB2 Protein
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Integrin beta 2 (ITGB2) (AA 1-769) protein (GST tag)
ITGB2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Integrin beta 2 (ITGB2) (AA 600-699) protein (GST tag)ITGB2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Integrin beta 2 (ITGB2) (AA 23-700) protein (His tag)Crystallography grade ITGB2 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Integrin beta 2 (ITGB2) (AA 24-702) protein (His tag)Crystallography grade ITGB2 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Integrin beta 2 (ITGB2) (AA 23-769) protein (rho-1D4 tag)Crystallography grade ITGB2 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Integrin beta 2 (ITGB2) (AA 24-771) protein (rho-1D4 tag)Crystallography grade ITGB2 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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: "Mutually Exclusive Roles of SHARPIN in Integrin Inactivation and NF-κB Signaling." in: PLoS ONE, Vol. 10, Issue 11, pp. e0143423, (2015) (PubMed).
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: "Mutually Exclusive Roles of SHARPIN in Integrin Inactivation and NF-κB Signaling." in: PLoS ONE, Vol. 10, Issue 11, pp. e0143423, (2015) (PubMed).
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- Target
- Integrin beta 2 (ITGB2)
- Alternative Name
- Cd18,itgb2 (ITGB2 Products)
- Synonyms
- CD18 Protein, LAD Protein, LCAMB Protein, LFA-1 Protein, MAC-1 Protein, MF17 Protein, MFI7 Protein, 2E6 Protein, AI528527 Protein, Cd18 Protein, Lfa1 Protein, ITGB2 Protein, itgb2 Protein, itgb2-a Protein, itgb2-b Protein, integrin subunit beta 2 Protein, integrin beta 2 Protein, integrin subunit beta 2 S homeolog Protein, ITGB2 Protein, Itgb2 Protein, itgb2.S Protein
- Background
- This gene encodes an integrin beta chain, which combines with multiple different alpha chains to form different integrin heterodimers. Integrins are integral cell-surface proteins that participate in cell adhesion as well as cell-surface mediated signalling. The encoded protein plays an important role in immune response and defects in this gene cause leukocyte adhesion deficiency. Alternative splicing results in multiple transcript variants.
- Molecular Weight
- 82.5 kDa
- NCBI Accession
- NP_001120963
- Pathways
- NF-kappaB Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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