ITGA5 Protein (GST tag)

Catalog No. ABIN2713732

Product Details

Target: ITGA5 (Integrin, alpha 5 (ITGA5))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This ITGA5 protein is labelled with GST tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human CD49e / ITGA5 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 95 % as determined by SDS-PAGE and Coomassie blue staining

Endotoxin Level: < 0.1 EU per μg protein as determined by LAL test

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the N-terminal.

Restrictions: For Research Use only

Handling

Buffer: Lyophilized from a 0.2 μM filtered solution of 20 mM Phosphate buffer, 150 mM NaCl, pH 7.2. Stable for at least 6 months from date of receipt under proper storage and handling conditions.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: ITGA5 (Integrin, alpha 5 (ITGA5))

Alternative Name: Cd49e,itga5 (ITGA5 Products)

Synonyms: ITGA5 Protein, Cd49e Protein, Fnra Protein, VLA5 Protein, CD49e Protein, FNRA Protein, VLA5A Protein, Itga5_retired Protein, integrin subunit alpha 5 Protein, integrin alpha 5 (fibronectin receptor alpha) Protein, ITGA5 Protein, Itga5 Protein

Background: The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.

Molecular Weight: 105.1 kDa

NCBI Accession: NP_002196

Pathways: Integrin Complex