CDC16 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2713829

Product Details

Target: CDC16 (Cell Division Cycle 16 Homolog (S. Cerevisiae) (CDC16))

Protein Type: Recombinant

Protein Characteristics: Transcript Variant 2

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This CDC16 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human CDC16 / APC6 (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: CDC16 (Cell Division Cycle 16 Homolog (S. Cerevisiae) (CDC16))

Alternative Name: Cdc16,apc6 (CDC16 Products)

Synonyms: zgc:123264 Protein, F9K20.19 Protein, F9K20_19 Protein, anaphase promoting complex 6 Protein, 2700071J12Rik Protein, 2810431D22Rik Protein, APC6 Protein, ANAPC6 Protein, CUT9 Protein, cell division cycle 16 Protein, cell division cycle 16 L homeolog Protein, cell division cycle 16 homolog (S. cerevisiae) Protein, cell division cycle protein 16 homolog Protein, anaphase promoting complex 6 Protein, CDC16 cell division cycle 16 Protein, CDC16 Protein, cdc16.L Protein, cdc16 Protein, LOC100434328 Protein, APC6 Protein, Cdc16 Protein

Background: The protein encoded by this gene functions as a protein ubiquitin ligase and is a component of the multiprotein APC complex. The APC complex is a cyclin degradation system that governs exit from mitosis by targeting cell cycle proteins for degredation by the 26S proteasome. Each component protein of the APC complex is highly conserved among eukaryotic organisms. This protein, and other APC complex proteins, contain a tetratricopeptide repeat (TPR) domain a protein domain that is often involved in protein-protein interactions and the assembly of multiprotein complexes. Multiple alternatively spliced transcript variants, encoding distinct proteins, have been identified.

Molecular Weight: 71.5 kDa

NCBI Accession: NP_001072113

Pathways: Regulation of Actin Filament Polymerization