CFHR1 Protein (His tag)

Catalog No. ABIN2713938

Product Details

Target: CFHR1 (Complement Factor H-Related 1 (CFHR1))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This CFHR1 protein is labelled with His tag.

Application: Antibody Production (AbP), Protein Interaction (PI), Standard (STD)

Specificity: Optimal preservation of protein structure, post-translational modifications and functions.

Characteristics:

• Recombinant human CFHR1 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 95 % as determined by SDS-PAGE and Coomassie blue staining

Endotoxin Level: Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
Protein-protein interaction
In vitro biochemical assays and cell-based functional assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Buffer: Lyophilized from a 0.2 μM filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/mL. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: CFHR1 (Complement Factor H-Related 1 (CFHR1))

Alternative Name: Cfhr1 (CFHR1 Products)

Synonyms: AI194696 Protein, CFHRB Protein, Cfhl1 Protein, CFHL Protein, CFHL1 Protein, CFHL1P Protein, CFHR1P Protein, FHR1 Protein, H36-1 Protein, H36-2 Protein, HFL1 Protein, HFL2 Protein, complement factor H-related 1 Protein, complement factor H-related protein 1 Protein, complement factor H related 1 Protein, Cfhr1 Protein, LOC735590 Protein, LOC746429 Protein, CFHR1 Protein

Background: This gene encodes a secreted protein belonging to the complement factor H protein family. It binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface, controlling complement, and facilitating tissue invasion. Mutations in this gene are associated with an increased risk of atypical hemolytic-uremic syndrome.

Molecular Weight: 36.78kD

NCBI Accession: NP_002104