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CHAC1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

CHAC1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2713951
  • Target See all CHAC1 Proteins
    CHAC1 (ChaC, Cation Transport Regulator Homolog 1 (CHAC1))
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 1
    Origin
    • 3
    • 1
    Human
    Source
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This CHAC1 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human CHAC1 (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product CHAC1 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    CHAC1 (ChaC, Cation Transport Regulator Homolog 1 (CHAC1))
    Alternative Name
    Chac1 (CHAC1 Products)
    Synonyms
    1810008K03Rik Protein, RGD1307153 Protein, ChaC glutathione specific gamma-glutamylcyclotransferase 1 Protein, ChaC, cation transport regulator 1 Protein, ChaC glutathione-specific gamma-glutamylcyclotransferase 1 Protein, CHAC1 Protein, Chac1 Protein
    Background
    This gene encodes a member of the gamma-glutamylcyclotransferase family of proteins. The encoded protein has been shown to promote neuronal differentiation by deglycination of the Notch receptor, which prevents receptor maturation and inhibits Notch signaling. This protein may also play a role in the unfolded protein response, and in regulation of glutathione levels and oxidative balance in the cell. Elevated expression of this gene may indicate increased risk of cancer recurrence among breast and ovarian cancer patients.
    Molecular Weight
    24.2 kDa
    NCBI Accession
    NP_077016
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