CHMP4A Protein (Myc-DYKDDDDK Tag)
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- Target See all CHMP4A Proteins
- CHMP4A (Charged Multivesicular Body Protein 4A (CHMP4A))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CHMP4A protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human CHMP4A protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product CHMP4A Protein
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Charged Multivesicular Body Protein 4A (CHMP4A) (AA 1-265) protein (His tag)
CHMP4A Origin: Human Host: Escherichia coli (E. coli) Recombinant SDS
Charged Multivesicular Body Protein 4A (CHMP4A) (AA 1-222) protein (Strep Tag)Crystallography grade CHMP4A Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- CHMP4A (Charged Multivesicular Body Protein 4A (CHMP4A))
- Alternative Name
- Chmp4a (CHMP4A Products)
- Synonyms
- C14orf123 Protein, CHMP4 Protein, CHMP4B Protein, HSPC134 Protein, SHAX2 Protein, SNF7 Protein, SNF7-1 Protein, VPS32-1 Protein, VPS32A Protein, charged multivesicular body protein 4A Protein, CHMP4A Protein
- Background
- CHMP4A belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).[supplied by OMIM, Mar 2008].
- Molecular Weight
- 29.6 kDa
- NCBI Accession
- NP_054888
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