CHMP4B Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2713984

Product Details

Target: CHMP4B (Charged Multivesicular Body Protein 4B (CHMP4B))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This CHMP4B protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human CHMP4B protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: CHMP4B (Charged Multivesicular Body Protein 4B (CHMP4B))

Alternative Name: Chmp4b (CHMP4B Products)

Synonyms: C20orf178 Protein, CHMP4A Protein, CTPP3 Protein, CTRCT31 Protein, SNF7 Protein, SNF7-2 Protein, Shax1 Protein, VPS32B Protein, Vps32-2 Protein, dJ553F4.4 Protein, 2010012F05Rik Protein, C76846 Protein, Snf7-2 Protein, RGD1309846 Protein, RGD1565889 Protein, CHMP4b Protein, chmp4b Protein, chmp4b.S Protein, CHMP4c Protein, c20orf178 Protein, wu:fc96b02 Protein, zgc:55566 Protein, charged multivesicular body protein 4B Protein, charged multivesicular body protein 4Ba Protein, charged multivesicular body protein 4B L homeolog Protein, charged multivesicular body protein 4Bb Protein, CHMP4B Protein, Chmp4b Protein, chmp4ba Protein, chmp4b.L Protein, chmp4bb Protein

Background: This gene encodes a member of the chromatin-modifying protein/charged multivesicular body protein (CHMP) protein family. The protein is part of the endosomal sorting complex required for transport (ESCRT) complex III (ESCRT-III), which functions in the sorting of endocytosed cell-surface receptors into multivesicular endosomes. The ESCRT machinery also functions in the final abscisson stage of cytokinesis and in the budding of enveloped viruses such as HIV-1. The three proteins of the CHMP4 subfamily interact with programmed cell death 6 interacting protein (PDCD6IP, also known as ALIX), which also functions in the ESCRT pathway. The CHMP4 proteins assemble into membrane-attached 5-nm filaments that form circular scaffolds and promote or stabilize outward budding. These polymers are proposed to help generate the luminal vesicles of multivesicular bodies. Mutations in this gene result in autosomal dominant posterior polar cataracts.[provided by RefSeq, Oct 2009].

Molecular Weight: 24.8 kDa

NCBI Accession: NP_789782