CIRH1A Protein (Myc-DYKDDDDK Tag)
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- Target See all CIRH1A Proteins
- CIRH1A (Cirrhosis, Autosomal Recessive 1A (Cirhin) (CIRH1A))
- Protein Type
- Recombinant
- Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CIRH1A protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Cirhin protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product CIRH1A Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- CIRH1A (Cirrhosis, Autosomal Recessive 1A (Cirhin) (CIRH1A))
- Alternative Name
- Cirhin (CIRH1A Products)
- Synonyms
- cirhin Protein, Cirhin Protein, Naic Protein, Teg-292 Protein, Tex292 Protein, naic Protein, tex292 Protein, zgc:77199 Protein, wu:fi09g10 Protein, wu:fi37c02 Protein, CIRH1A Protein, CIRHIN Protein, NAIC Protein, TEX292 Protein, UTP4 Protein, UTP4, small subunit processome component Protein, UTP4 small subunit processome component Protein, UTP4 small subunit processome component L homeolog Protein, UTP4 Protein, Utp4 Protein, utp4 Protein, utp4.L Protein
- Background
- This gene encodes a WD40-repeat-containing protein that is localized to the nucleolus. Mutation of this gene causes North American Indian childhood cirrhosis, a severe intrahepatic cholestasis that results in transient neonatal jaundice, and progresses to periportal fibrosis and cirrhosis in childhood and adolescence. Alternative splicing results in multiple transcript variants.
- Molecular Weight
- 76.7 kDa
- NCBI Accession
- NP_116219
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