HSD11B2 Protein (Myc-DYKDDDDK Tag)
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- Target See all HSD11B2 Proteins
- HSD11B2 (Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This HSD11B2 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human 11-beta HSD2 / HSD11B2 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product HSD11B2 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- HSD11B2 (Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2))
- Alternative Name
- 11-beta Hsd2,hsd11b2 (HSD11B2 Products)
- Synonyms
- MGC81883 Protein, 11-HSD2 Protein, AME Protein, AME1 Protein, HSD11K Protein, HSD2 Protein, SDR9C3 Protein, 11HSD2 Protein, HSD11B2 Protein, hydroxysteroid (11-beta) dehydrogenase 2 L homeolog Protein, hydroxysteroid 11-beta dehydrogenase 2 Protein, hsd11b2.L Protein, HSD11B2 Protein, Hsd11b2 Protein
- Background
- Catalyzes the conversion of cortisol to the inactive metabolite cortisone. Modulates intracellular glucocorticoid levels, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids. [UniProtKB/Swiss-Prot Function]
- Molecular Weight
- 43.9 kDa
- NCBI Accession
- NP_000187
- Pathways
- Steroid Hormone Biosynthesis, Regulation of Systemic Arterial Blood Pressure by Hormones
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