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ABAT Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

ABAT Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2714259
  • Target See all ABAT Proteins
    ABAT (4-Aminobutyrate Aminotransferase (ABAT))
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 2
    Origin
    • 5
    • 2
    • 2
    • 1
    • 1
    Human
    Source
    • 3
    • 3
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This ABAT protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human ABAT (transcript variant 2) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product ABAT Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    ABAT (4-Aminobutyrate Aminotransferase (ABAT))
    Alternative Name
    Abat (ABAT Products)
    Synonyms
    cb880 Protein, fj82a01 Protein, wu:fj82a01 Protein, BA0325 Protein, PSPTO0259 Protein, PSPTO0301 Protein, PSPTO1890 Protein, GABA-AT Protein, GABAT Protein, NPD009 Protein, GABA-T Protein, L-AIBAT Protein, 9630038C02Rik Protein, AI255750 Protein, ENSMUSG00000051226 Protein, Gabaat Protein, Gabat Protein, Gm9851 Protein, I54 Protein, Laibat Protein, X61497 Protein, beta-AlaAT Protein, 4-aminobutyrate aminotransferase Protein, 4-aminobutyrate--2-oxoglutarate transaminase Protein, GABA aminotransferase PLP-dependent PuuE Protein, 4-aminobutyrate aminotransferase, mitochondrial Protein, aspartate aminotransferase family protein Protein, 4-aminobutyrate aminotransferase S homeolog Protein, ABAT Protein, abat Protein, gabT Protein, puuE Protein, gabT-1 Protein, gabT-2 Protein, gabT-3 Protein, CNE01830 Protein, Mmwyl1_0047 Protein, CpipJ_CPIJ008729 Protein, KCR_RS04555 Protein, Bcenmc03_4909 Protein, Hden_0972 Protein, Dbac_2000 Protein, Mesil_2400 Protein, Trad_0121 Protein, abat.S Protein, Abat Protein
    Background
    4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50-kD subunits complexed to pyridoxal-5-phosphate. The protein sequence is over 95 % similar to the pig protein. GABA is estimated to be present in nearly one-third of human synapses. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.
    Molecular Weight
    53.2 kDa
    NCBI Accession
    NP_000654
    Pathways
    Monocarboxylic Acid Catabolic Process
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