ADAR Protein (Transcript Variant 4) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2714393

Product Details

Target: ADAR (Adenosine Deaminase, RNA-Specific (ADAR))

Protein Type: Recombinant

Protein Characteristics: Transcript Variant 4

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This ADAR protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human ADAR1 / DRADA (transcript variant 4) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: ADAR (Adenosine Deaminase, RNA-Specific (ADAR))

Alternative Name: Adar1,drada (ADAR Products)

Synonyms: red1 Protein, drada Protein, wu:fc22a02 Protein, adar1 Protein, dsRAD Protein, dsRAD-1 Protein, ADAR Protein, ADAR1 Protein, CG12598 Protein, Dmel\\CG12598 Protein, EG:BACN35H14.1 Protein, adar Protein, adr Protein, cg12598 Protein, dADAR Protein, dAdar Protein, hypnos-2 Protein, NV18763 Protein, AGS6 Protein, DRADA Protein, DSH Protein, DSRAD Protein, G1P1 Protein, IFI-4 Protein, IFI4 Protein, K88DSRBP Protein, P136 Protein, AV242451 Protein, Adar1 Protein, mZaADAR Protein, adenosine deaminase, RNA-specific Protein, adenosine deaminase, RNA-specific S homeolog Protein, adenosine deaminase, RNA specific Protein, Adenosine deaminase acting on RNA Protein, adenosine deaminase acting on RNA Protein, double-stranded RNA-specific editase 1 Protein, adar Protein, adar.S Protein, ADAR Protein, Adar Protein, CpipJ_CPIJ011849 Protein, LOC100114127 Protein

Background: This gene encodes the enzyme responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double-stranded RNA through conversion of adenosine to inosine. Mutations in this gene have been associated with dyschromatosis symmetrica hereditaria. Alternative splicing results in multiple transcript variants.

Molecular Weight: 103.5 kDa

NCBI Accession: NP_001020278

Pathways: Protein targeting to Nucleus