AGL Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2714455

Product Details

Target: AGL (Amylo-alpha-1, 6-Glucosidase, 4-alpha-Glucanotransferase (AGL))

Protein Type: Recombinant

Protein Characteristics: Transcript Variant 3

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This AGL protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human AGL / GDE (transcript variant 3) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: AGL (Amylo-alpha-1, 6-Glucosidase, 4-alpha-Glucanotransferase (AGL))

Alternative Name: Agl,gde (AGL Products)

Synonyms: DDBDRAFT_0219237 Protein, DDBDRAFT_0234114 Protein, DDB_0219237 Protein, DDB_0234114 Protein, GDE Protein, 1110061O17Rik Protein, 9430004C13Rik Protein, 9630046L06Rik Protein, AI850929 Protein, C77197 Protein, amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase Protein, glycogen debranching enzyme Protein, glycogen debranching protein Protein, amylo-1,6-glucosidase, 4-alpha-glucanotransferase Protein, AGL Protein, agl Protein, MMAH_RS03870 Protein, Agl Protein

Background: This gene encodes the glycogen debrancher enzyme which is involved in glycogen degradation. This enzyme has two independent catalytic activities which occur at different sites on the protein: a 4-alpha-glucotransferase activity and a amylo-1,6-glucosidase activity. Mutations in this gene are associated with glycogen storage disease although a wide range of enzymatic and clinical variability occurs which may be due to tissue-specific alternative splicing. Alternatively spliced transcripts encoding different isoforms have been described.

Molecular Weight: 174.6 kDa

NCBI Accession: NP_000634

Pathways: Cellular Glucan Metabolic Process