P5CS Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2714537

Product Details

Target: P5CS (ALDH18A1) (Aldehyde Dehydrogenase 18 Family, Member A1 (ALDH18A1))

Protein Type: Recombinant

Protein Characteristics: Transcript Variant 1

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This P5CS protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human ALDH18A1 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: P5CS (ALDH18A1) (Aldehyde Dehydrogenase 18 Family, Member A1 (ALDH18A1))

Alternative Name: Aldh18a1 (ALDH18A1 Products)

Synonyms: ALDH18A1 Protein, ARCL3A Protein, GSAS Protein, P5CS Protein, PYCS Protein, 2810433K04Rik Protein, AI429789 Protein, Pycs Protein, cb842 Protein, cb899 Protein, pycs Protein, sb:cb881 Protein, wu:fa91f10 Protein, wu:fi05f11 Protein, wu:fi17d12 Protein, aldehyde dehydrogenase 18 family member A1 Protein, aldehyde dehydrogenase 18 family, member A1 Protein, aldehyde dehydrogenase 18 family member A1 L homeolog Protein, ALDH18A1 Protein, aldh18a1 Protein, Aldh18a1 Protein, aldh18a1.L Protein

Background: This gene is a member of the aldehyde dehydrogenase family and encodes a bifunctional ATP- and NADPH-dependent mitochondrial enzyme with both gamma-glutamyl kinase and gamma-glutamyl phosphate reductase activities. The encoded protein catalyzes the reduction of glutamate to delta1-pyrroline-5-carboxylate, a critical step in the de novo biosynthesis of proline, ornithine and arginine. Mutations in this gene lead to hyperammonemia, hypoornithinemia, hypocitrullinemia, hypoargininemia and hypoprolinemia and may be associated with neurodegeneration, cataracts and connective tissue diseases. Alternatively spliced transcript variants, encoding different isoforms, have been described for this gene.

Molecular Weight: 87.1 kDa

NCBI Accession: NP_002851