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ALDH8A1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

ALDH8A1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2714552
  • Target See all ALDH8A1 Proteins
    ALDH8A1 (Aldehyde Dehydrogenase 8 Family, Member A1 (ALDH8A1))
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 1
    Origin
    • 3
    • 1
    • 1
    Human
    Source
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This ALDH8A1 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human ALDH8A1 / ALDH12 (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product ALDH8A1 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    ALDH8A1 (Aldehyde Dehydrogenase 8 Family, Member A1 (ALDH8A1))
    Alternative Name
    Aldh8a1,aldh12 (ALDH8A1 Products)
    Synonyms
    zgc:92068 Protein, wu:fi34g05 Protein, ALDH8A1 Protein, ALDH12 Protein, DJ352A20.2 Protein, Raldh4 Protein, aldehyde dehydrogenase 8 family member A1 Protein, aldehyde dehydrogenase 8 family, member A1 Protein, ALDH8A1 Protein, aldh8a1 Protein, Aldh8a1 Protein
    Background
    This protein belongs to the aldehyde dehydrogenases family of proteins. It plays a role in a pathway of 9-cis-retinoic acid biosynthesis in vivo. This enzyme converts 9-cis-retinal into the retinoid X receptor ligand 9-cis-retinoic acid, and has approximately 40-fold higher activity with 9-cis-retinal than with all-trans-retinal. Therefore, it is the first known aldehyde dehydrogenase to show a preference for 9-cis-retinal relative to all-trans-retinal. Three transcript variants encoding distinct protein isoforms have been identified for this gene.
    Molecular Weight
    53.2 kDa
    NCBI Accession
    NP_072090
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