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ALOX5AP Protein (Myc-DYKDDDDK Tag)

ALOX5AP Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2714586
  • Target See all ALOX5AP Proteins
    ALOX5AP (Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP))
    Protein Type
    Recombinant
    Origin
    • 3
    • 1
    Human
    Source
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This ALOX5AP protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human ALOX5AP / FLAP protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product ALOX5AP Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    ALOX5AP (Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP))
    Alternative Name
    Alox5ap,flap (ALOX5AP Products)
    Synonyms
    fj65d02 Protein, zgc:63982 Protein, wu:fj65d02 Protein, flap Protein, al5ap Protein, Alox5ap Protein, ALOX5AP Protein, Flap Protein, FLAP Protein, arachidonate 5-lipoxygenase-activating protein Protein, arachidonate 5-lipoxygenase activating protein Protein, alox5ap Protein, ALOX5AP Protein, Alox5ap Protein
    Background
    This gene encodes a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
    Molecular Weight
    18 kDa
    NCBI Accession
    NP_001620
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