alpha Adducin Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Target See all alpha Adducin (ADD1) Proteins
- alpha Adducin (ADD1) (Adducin 1 (Alpha) (ADD1))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This alpha Adducin protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Alpha-Adducin / ADD1 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product ADD1 Protein
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Adducin 1 (Alpha) (ADD1) (AA 1-662) protein (GST tag)
ADD1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Adducin 1 (Alpha) (ADD1) (AA 1-737) protein (Strep Tag)Crystallography grade ADD1 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Adducin 1 (Alpha) (ADD1) (AA 1-735) protein (Strep Tag)Crystallography grade ADD1 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- alpha Adducin (ADD1) (Adducin 1 (Alpha) (ADD1))
- Alternative Name
- alpha-Adducin (Add1) (ADD1 Products)
- Synonyms
- ADDA Protein, AI256389 Protein, alpha-adducin Protein, bZ1H20.1 Protein, cb787 Protein, zgc:158352 Protein, add2 Protein, adda Protein, add1-a Protein, ADD1 Protein, adducin 1 Protein, adducin 1 (alpha) Protein, adducin 1 S homeolog Protein, ADD1 Protein, Add1 Protein, add1 Protein, add1.S Protein
- Background
- Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms however, not all variants have been fully described.
- Molecular Weight
- 80.8 kDa
- NCBI Accession
- NP_001110
- Pathways
- Negative Regulation of Hormone Secretion, Regulation of Actin Filament Polymerization, Regulation of Lipid Metabolism by PPARalpha, ER-Nucleus Signaling
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