Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

Ensa Protein (Transcript Variant 8) (Myc-DYKDDDDK Tag)

ENSA Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2714623
  • Target See all Ensa (ENSA) Proteins
    Ensa (ENSA) (Endosulfine alpha (ENSA))
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 8
    Origin
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 8
    • 6
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This Ensa protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human Alpha-endosulfine / ENSA (transcript variant 8) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product ENSA Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    Ensa (ENSA) (Endosulfine alpha (ENSA))
    Alternative Name
    alpha-Endosulfine (Ensa) (ENSA Products)
    Synonyms
    ARPP-19e Protein, 1700020C18Rik Protein, 2610007F17Rik Protein, AI451924 Protein, ensa Protein, si:dkeyp-24a7.3 Protein, ensaa Protein, endosulfine alpha Protein, endosulfine alpha a Protein, endosulfine alpha S homeolog Protein, ENSA Protein, Ensa Protein, ensa Protein, ensaa Protein, ensa.S Protein
    Background
    The protein encoded by this gene belongs to a highly conserved cAMP-regulated phosphoprotein (ARPP) family. This protein was identified as an endogenous ligand for the sulfonylurea receptor, ABCC8/SUR1. ABCC8 is the regulatory subunit of the ATP-sensitive potassium (KATP) channel, which is located on the plasma membrane of pancreatic beta cells and plays a key role in the control of insulin release from pancreatic beta cells. This protein is thought to be an endogenous regulator of KATP channels. In vitro studies have demonstrated that this protein modulates insulin secretion through the interaction with KATP channel, and this gene has been proposed as a candidate gene for type 2 diabetes. At least eight alternatively spliced transcript variants encoding distinct isoforms have been observed.
    Molecular Weight
    11.8 kDa
    NCBI Accession
    NP_997051
You are here:
Support