ASCL1 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2714974

Product Details

Target: ASCL1 (Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This ASCL1 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human ASCL1 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: ASCL1 (Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1))

Alternative Name: Ascl1 (ASCL1 Products)

Synonyms: ASH1 Protein, HASH1 Protein, MASH1 Protein, bHLHa46 Protein, AI225900 Protein, Mash1 Protein, ASCL1 Protein, Zash-1a Protein, ash Protein, asha Protein, id:ibd5085 Protein, im:7138587 Protein, si:dkey-264k15.2 Protein, zash1a Protein, zasha Protein, Xash1 Protein, ascl1-A Protein, Zash-1b Protein, ashb Protein, zashb Protein, achaete-scute family bHLH transcription factor 1 Protein, achaete-scute family bHLH transcription factor 1a Protein, achaete-scute family bHLH transcription factor 1 L homeolog Protein, achaete-scute complex homolog 1 Protein, achaete-scute family bHLH transcription factor 1b Protein, ASCL1 Protein, Ascl1 Protein, ascl1a Protein, ascl1.L Protein, LOC100220505 Protein, ascl1b Protein

Background: This gene encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases.

Molecular Weight: 25.3 kDa

NCBI Accession: NP_004307

Pathways: Dopaminergic Neurogenesis