ASPSCR1 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2715005

Product Details

Target: ASPSCR1 (Alveolar Soft Part Sarcoma Chromosome Region, Candidate 1 (ASPSCR1))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This ASPSCR1 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human ASPSCR1 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: ASPSCR1 (Alveolar Soft Part Sarcoma Chromosome Region, Candidate 1 (ASPSCR1))

Alternative Name: Aspscr1 (ASPSCR1 Products)

Synonyms: tug Protein, aspl Protein, asps Protein, rcc17 Protein, ubxd9 Protein, aspcr1 Protein, ASPCR1 Protein, ASPL Protein, ASPS Protein, RCC17 Protein, TUG Protein, UBXD9 Protein, UBXN9 Protein, 1190006K01Rik Protein, ASPC Protein, ASPSCR1, UBX domain containing tether for SLC2A4 Protein, alveolar soft part sarcoma chromosome region, candidate 1 S homeolog Protein, alveolar soft part sarcoma chromosome region, candidate 1 Protein, alveolar soft part sarcoma chromosome region, candidate 1 (human) Protein, ASPSCR1 Protein, aspscr1.S Protein, Aspscr1 Protein, aspscr1 Protein, Bm1_55980 Protein

Background: The protein encoded by this gene contains a UBX domain and interacts with glucose transporter type 4 (GLUT4). This protein is a tether, which sequesters the GLUT4 in intracellular vesicles in muscle and fat cells in the absence of insulin, and redistributes the GLUT4 to the plasma membrane within minutes of insulin stimulation. Translocation t(X17)(p11q25) of this gene with transcription factor TFE3 gene results in a ASPSCR1-TFE3 fusion protein in alveolar soft part sarcoma and in renal cell carcinomas. Multiple alternatively spliced transcript variants have been found.

Molecular Weight: 60 kDa

NCBI Accession: NP_076988