ATP6V1B2 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2715056

Product Details

Target: ATP6V1B2 (ATPase, H+ Transporting, Lysosomal 56/58kDa, V1 Subunit B2 (ATP6V1B2))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This ATP6V1B2 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human ATP6V1B2 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: ATP6V1B2 (ATPase, H+ Transporting, Lysosomal 56/58kDa, V1 Subunit B2 (ATP6V1B2))

Alternative Name: Atp6v1b2 (ATP6V1B2 Products)

Synonyms: Atp6b1b2 Protein, Atp6b2 Protein, Vatb Protein, vha55 Protein, VATB Protein, ATP6B1B2 Protein, ATP6B2 Protein, HO57 Protein, VPP3 Protein, Vma2 Protein, atp6v1bb Protein, fj51e01 Protein, vatB2 Protein, wu:fj51e01 Protein, zgc:109771 Protein, AI194269 Protein, AI790362 Protein, R74844 Protein, ATPase H+ transporting V1 subunit B2 Protein, ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 S homeolog Protein, ATPase, H+ transporting, lysosomal, V1 subunit B2 Protein, ATPase, H+ transporting, lysosomal V1 subunit B2 Protein, Atp6v1b2 Protein, atp6v1b2.S Protein, ATP6V1B2 Protein, atp6v1b2 Protein

Background: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. The protein encoded by this gene is one of two V1 domain B subunit isoforms and is the only B isoform highly expressed in osteoclasts.

Molecular Weight: 56.3 kDa

NCBI Accession: NP_001684

Pathways: Transition Metal Ion Homeostasis, Proton Transport