BCDIN3D Protein (Myc-DYKDDDDK Tag)
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- Target See all BCDIN3D Proteins
- BCDIN3D (BCDIN3 Domain Containing (BCDIN3D))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This BCDIN3D protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human BCDIN3D protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product BCDIN3D Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- BCDIN3D (BCDIN3 Domain Containing (BCDIN3D))
- Alternative Name
- Bcdin3d (BCDIN3D Products)
- Synonyms
- 4930556P03Rik Protein, AV138748 Protein, BCDIN3 domain containing RNA methyltransferase Protein, BCDIN3 domain containing Protein, BCDIN3D Protein, Bcdin3d Protein
- Background
- This gene encodes an RNA methyltransferase which belongs to the rossmann fold methyltransferase family, and serves as a 5&apos-methylphosphate capping enzyme that is specific for cytoplasmic histidyl tRNA. The encoded protein contains an S-adenosylmethionine binding domain and uses the methyl group donor, S-adenosylmethionine. This gene is overexpressed in breast cancer cells, and is related to the tumorigenic phenotype and poor prognosis of breast cancer. The encoded protein is thought to promote the cellular invasion of breast cancer cells, by downregulating the expression of tumor suppressor miRNAs through the dimethylation of the 5-monophosphate of the corresponding precursor miRNAs.
- Molecular Weight
- 33 kDa
- NCBI Accession
- NP_859059
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