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BCDIN3D Protein (Myc-DYKDDDDK Tag)

BCDIN3D Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2715187
  • Target See all BCDIN3D Proteins
    BCDIN3D (BCDIN3 Domain Containing (BCDIN3D))
    Protein Type
    Recombinant
    Origin
    • 2
    • 1
    • 1
    Human
    Source
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This BCDIN3D protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human BCDIN3D protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product BCDIN3D Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    BCDIN3D (BCDIN3 Domain Containing (BCDIN3D))
    Alternative Name
    Bcdin3d (BCDIN3D Products)
    Synonyms
    4930556P03Rik Protein, AV138748 Protein, BCDIN3 domain containing RNA methyltransferase Protein, BCDIN3 domain containing Protein, BCDIN3D Protein, Bcdin3d Protein
    Background
    This gene encodes an RNA methyltransferase which belongs to the rossmann fold methyltransferase family, and serves as a 5&apos-methylphosphate capping enzyme that is specific for cytoplasmic histidyl tRNA. The encoded protein contains an S-adenosylmethionine binding domain and uses the methyl group donor, S-adenosylmethionine. This gene is overexpressed in breast cancer cells, and is related to the tumorigenic phenotype and poor prognosis of breast cancer. The encoded protein is thought to promote the cellular invasion of breast cancer cells, by downregulating the expression of tumor suppressor miRNAs through the dimethylation of the 5-monophosphate of the corresponding precursor miRNAs.
    Molecular Weight
    33 kDa
    NCBI Accession
    NP_859059
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