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Bestrophin 3 Protein (BEST3) (Transcript Variant 2) (Myc-DYKDDDDK Tag)

BEST3 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2715225
  • Target See all Bestrophin 3 (BEST3) Proteins
    Bestrophin 3 (BEST3)
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 2
    Origin
    • 4
    • 3
    • 1
    • 1
    Human
    Source
    • 2
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This Bestrophin 3 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human Bestrophin-3 (transcript variant 2) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product BEST3 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    Bestrophin 3 (BEST3)
    Alternative Name
    Bestrophin-3 (BEST3 Products)
    Synonyms
    CG12327 Protein, Dmel\\CG12327 Protein, dbest3 Protein, best-3 Protein, BEST3 Protein, VMD2L3 Protein, Vmd2l3 Protein, mBest4 Protein, bestrophin-3 Protein, bestrophin 3 Protein, Bestrophin 3 Protein, BEST3 Protein, Best3 Protein, best3 Protein
    Background
    BEST3 belongs to the bestrophin family of anion channels, which includes BEST1 (MIM 607854), the gene mutant in vitelliform macular dystrophy (VMD MIM 153700), and 2 other BEST1-like genes, BEST2 (MIM 607335) and BEST4 (MIM 607336). Bestrophins are transmembrane (TM) proteins that share a homology region containing a high content of aromatic residues, including an invariant arg-phe-pro (RFP) motif. The bestrophin genes share a conserved gene structure, with almost identical sizes of the 8 RFP-TM domain-encoding exons and highly conserved exon-intron boundaries. Each of the 4 bestrophin genes has a unique 3-prime end of variable length (Stohr et al., 2002 [PubMed 12032738] Tsunenari et al., 2003 [PubMed 12907679]).[supplied by OMIM, Mar 2008].
    Molecular Weight
    50.8 kDa
    NCBI Accession
    NP_689652
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