BIN1 Protein (Transcript Variant 9) (Myc-DYKDDDDK Tag)
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- Target See all BIN1 Proteins
- BIN1 (Bridging Integrator 1 (BIN1))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 9
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This BIN1 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human BIN1 / AMPHL (transcript variant 9) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product BIN1 Protein
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Bridging Integrator 1 (BIN1) (Transcript Variant 8) protein (Myc-DYKDDDDK Tag)
BIN1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Bridging Integrator 1 (BIN1) (AA 1-439) protein (GST tag)BIN1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Bridging Integrator 1 (BIN1) (AA 355-454) protein (GST tag)BIN1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Bridging Integrator 1 (BIN1) (AA 1-439) protein (His tag)BIN1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % by SDS – PAGE SDS
Bridging Integrator 1 (BIN1) (AA 2-593) protein (His tag)Crystallography grade BIN1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Bridging Integrator 1 (BIN1) (AA 2-588) protein (His tag)Crystallography grade BIN1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Bridging Integrator 1 (BIN1) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)BIN1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- BIN1 (Bridging Integrator 1 (BIN1))
- Alternative Name
- Bin1,amphl (BIN1 Products)
- Synonyms
- bin1 Protein, MGC53185 Protein, amph2 Protein, amphl Protein, sh3p9 Protein, MGC76187 Protein, cb57 Protein, zgc:86701 Protein, BIN1 Protein, AMPH2 Protein, AMPHL Protein, SH3P9 Protein, ALP-1 Protein, Amphl Protein, BRAMP-2 Protein, bridging integrator 1 Protein, bridging integrator 1 S homeolog Protein, bridging integrator 1b Protein, BIN1 Protein, bin1.S Protein, bin1 Protein, bin1b Protein, Bin1 Protein
- Background
- This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynamin, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene results in several transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described.
- Molecular Weight
- 48.1 kDa
- NCBI Accession
- NP_647600
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