BMX Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
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- Target See all BMX Proteins
- BMX (BMX Non-Receptor Tyrosine Kinase (BMX))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- Transcript Variant 2
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This BMX protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Functional Studies (Func), Antibody Production (AbP), Standard (STD), Protein Interaction (PI)
- Specificity
- Optimal preservation of protein structure, post-translational modifications and functions.
- Characteristics
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- Recombinant human BMX (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Tested for bioactivity.
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Biological Activity Comment
- BMX activity verified in a biochemical assay:,BMX activity verified in a biochemical assay:
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BMX Non-Receptor Tyrosine Kinase (BMX) (AA 150-280) protein (GST tag)
BMX Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
BMX Non-Receptor Tyrosine Kinase (BMX) (AA 1-675) protein (Strep Tag)Crystallography grade BMX Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
BMX Non-Receptor Tyrosine Kinase (BMX) (AA 1-651) protein (Strep Tag)Crystallography grade BMX Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
BMX Non-Receptor Tyrosine Kinase (BMX) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)BMX Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
Protein-protein interaction
In vitro biochemical assays and cell-based functional assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- > 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- BMX (BMX Non-Receptor Tyrosine Kinase (BMX))
- Alternative Name
- Bmx (BMX Products)
- Synonyms
- BMX Protein, ETK Protein, PSCTK2 Protein, PSCTK3 Protein, Etk Protein, Etk/Bmx Protein, Tyro8 Protein, RGD1565643 Protein, BMX non-receptor tyrosine kinase Protein, BMX Protein, bmx Protein, Bmx Protein
- Background
- This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Alternatively spliced transcript variants have been found for this gene.
- Molecular Weight
- 77.8 kDa
- NCBI Accession
- NP_001712
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