BTN3A2 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2715355

Product Details

Target: BTN3A2 (Butyrophilin, Subfamily 3, Member A2 (BTN3A2))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This BTN3A2 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human BTN3A2 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

References

Shiryaev, Aleshin, Muranaka, Kukreja, Routenberg, Remacle, Liddington, Cieplak, Kozlov, Strongin: "Structural and functional diversity of metalloproteinases encoded by the Bacteroides fragilis pathogenicity island." in: The FEBS journal, Vol. 281, Issue 11, pp. 2487-502, (2014) (PubMed).

Ge, Siegel, Jordan, Naumann: "Ligand binding alters dimerization and sequestering of urokinase receptors in raft-mimicking lipid mixtures." in: Biophysical journal, Vol. 107, Issue 9, pp. 2101-11, (2014) (PubMed).

Garcia-Sanz, Quintanilla, Lafita, Moreno-Bueno, García-Gutierrez, Tabor, Varela, Shiio, Larsson, Portillo, Leon: "Sin3b interacts with Myc and decreases Myc levels." in: The Journal of biological chemistry, Vol. 289, Issue 32, pp. 22221-36, (2014) (PubMed).

Wang, Henry, Distefano, Wang, Räikkönen, Mönkkönen, Tanaka, Morita: "Butyrophilin 3A1 plays an essential role in prenyl pyrophosphate stimulation of human V?2V?2 T cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 191, Issue 3, pp. 1029-42, (2013) (PubMed).

Bardeleben, Sharma, Reeve, Bassilian, Frost, Hoang, Shi, Lichtenstein: "Metabolomics identifies pyrimidine starvation as the mechanism of 5-aminoimidazole-4-carboxamide-1-β-riboside-induced apoptosis in multiple myeloma cells." in: Molecular cancer therapeutics, Vol. 12, Issue 7, pp. 1310-21, (2013) (PubMed).

Choudhury, de Lima Alves, de Andrés-Aguayo, Graf, Cáceres, Rappsilber, Michlewski: "Tissue-specific control of brain-enriched miR-7 biogenesis." in: Genes & development, Vol. 27, Issue 1, pp. 24-38, (2013) (PubMed).

Target Details

Target: BTN3A2 (Butyrophilin, Subfamily 3, Member A2 (BTN3A2))

Alternative Name: Btn3a2 (BTN3A2 Products)

Synonyms: BT3.2 Protein, BTF4 Protein, CD277 Protein, butyrophilin subfamily 3 member A2 Protein, butyrophilin-like protein 1 Protein, butyrophilin subfamily 1 member A1 Protein, BTN3A2 Protein, LOC481727 Protein, LOC615223 Protein, LOC100599692 Protein

Background: This gene encodes a member of the immunoglobulin superfamily, which resides in the juxta-telomeric region of the major histocompatability class 1 locus and is clustered with the other family members on chromosome 6. The encoded protein may be involved in the adaptive immune response. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 33.2 kDa

NCBI Accession: NP_008978