CHTOP Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2715454

Product Details

Target: CHTOP (Chromatin Target of PRMT1 (CHTOP))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This CHTOP protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human C1orf77 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: CHTOP (Chromatin Target of PRMT1 (CHTOP))

Alternative Name: c1orf77 (CHTOP Products)

Synonyms: C1orf77 Protein, FL-SRAG Protein, FOP Protein, RP1-178F15.2 Protein, SRAG Protein, SRAG-3 Protein, SRAG-5 Protein, pp7704 Protein, 2500003M10Rik Protein, C81330 Protein, Fop Protein, Srag Protein, C25H1orf77 Protein, C3H1orf77 Protein, c1orf77 Protein, chtop Protein, fop Protein, srag Protein, fb17a05 Protein, wu:fb17a05 Protein, wu:fi05e09 Protein, zgc:55292 Protein, zgc:153909 Protein, chromatin target of PRMT1 Protein, chromatin target of PRMT1 S homeolog Protein, chromatin target of PRMT1 protein Protein, chromatin target of PRMT1a Protein, chromatin target of PRMT1b Protein, CHTOP Protein, Chtop Protein, chtop.S Protein, LOC100344922 Protein, chtopa Protein, chtopb Protein

Background: This gene encodes a small nuclear protein that is characterized by an arginine and glycine rich region. This protein may have an important role in the regulation of fetal globin gene expression and in the activation of estrogen-responsive genes. A recent study reported that this protein binds 5-hydroxymethylcytosine (5hmC) and associates with an arginine methyltransferase complex (methylosome), which promotes methylation of arginine 3 of histone H4 (H4R3) and activation of genes involved in glioblastomagenesis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Molecular Weight: 26.2 kDa

NCBI Accession: NP_056422