APITD1 Protein (Transcript Variant B) (Myc-DYKDDDDK Tag)
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- Target See all APITD1 Proteins
- APITD1 (Apoptosis-Inducing, TAF9-Like Domain 1 (APITD1))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant B
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This APITD1 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Apoptosis-inducing, TAF9-like domain 1 (APITD1), transcript variant B (transcript variant B) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product APITD1 Protein
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Apoptosis-Inducing, TAF9-Like Domain 1 (APITD1) (AA 1-138) protein (GST tag)
APITD1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Apoptosis-Inducing, TAF9-Like Domain 1 (APITD1) (AA 1-138) protein (Strep Tag)Crystallography grade APITD1 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Apoptosis-Inducing, TAF9-Like Domain 1 (APITD1) (AA 1-142) protein (Strep Tag)Crystallography grade APITD1 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- APITD1 (Apoptosis-Inducing, TAF9-Like Domain 1 (APITD1))
- Abstract
- APITD1 Products
- Synonyms
- CENP-S Protein, CENPS Protein, FAAP16 Protein, MHF1 Protein, 2610040C18Rik Protein, 2810407L01Rik Protein, cenps Protein, mhf1 Protein, APITD1 Protein, Apitd1 Protein, Mhf1 Protein, apitd1 Protein, zgc:194319 Protein, centromere protein S Protein, apoptosis-inducing, TAF9-like domain 1 Protein, centromere protein S L homeolog Protein, CENPS Protein, Cenps Protein, cenps.L Protein, APITD1 Protein, cenps Protein
- Background
- This gene was identified in the neuroblastoma tumor suppressor candidate region on chromosome 1p36. It contains a TFIID-31 domain, similar to that found in TATA box-binding protein-associated factor, TAF(II)31, which is required for p53-mediated transcription activation. This gene was expressed at very low levels in neuroblastoma tumors, and was shown to reduce cell growth in neuroblastoma cells, suggesting that it may have a role in a cell death pathway. The protein is a component of multiple complexes, including the Fanconi anemia (FA) core complex, the APITD1/CENPS complex, and the CENPA-CAD (nucleosome distal) complex. Known functions include an involvement with chromatin associations of the FA core complex, and a role in the stable assembly of the outer kinetochore. Alternative splicing of this gene results in multiple transcript variants. Naturally occurring read-through transcripts also exist between this gene and the downstream cortistatin (CORT) gene, as represented in GeneID:100526739. An APITD1-related pseudogene has been identified on chromosome 7.
- Molecular Weight
- 11.1 kDa
- NCBI Accession
- NP_954992
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