COQ6 Protein (His tag)
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- Target See all COQ6 Proteins
- COQ6 (Coenzyme Q6, Monooxygenase (COQ6))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This COQ6 protein is labelled with His tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human COQ6 (N-term HIS tag, transcript variant 1) protein expressed in E. coli.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product COQ6 Protein
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Coenzyme Q6, Monooxygenase (COQ6) (AA 1-468) protein (GST tag)
COQ6 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Coenzyme Q6, Monooxygenase (COQ6) (AA 29-468) protein (His tag)Crystallography grade COQ6 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Coenzyme Q6, Monooxygenase (COQ6) (AA 36-476) protein (His tag)Crystallography grade COQ6 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the N-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- COQ6 (Coenzyme Q6, Monooxygenase (COQ6))
- Alternative Name
- Coenzyme q6 Homolog, Monooxygenase (S. Cerevisiae) (Coq6) (COQ6 Products)
- Synonyms
- CGI10 Protein, COQ10D6 Protein, 5930427M12Rik Protein, AW742344 Protein, zgc:153379 Protein, coq6 Protein, coenzyme Q6, monooxygenase Protein, coenzyme Q6 monooxygenase Protein, Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial Protein, coenzyme Q6 monooxygenase L homeolog Protein, COQ6 Protein, Coq6 Protein, coq-6 Protein, coq6 Protein, coq6.L Protein
- Background
- The protein encoded by this gene belongs to the ubiH/COQ6 family. It is an evolutionarily conserved monooxygenase required for the biosynthesis of coenzyme Q10 (or ubiquinone), which is an essential component of the mitochondrial electron transport chain, and one of the most potent lipophilic antioxidants implicated in the protection of cell damage by reactive oxygen species. Knockdown of this gene in mouse and zebrafish results in decreased growth due to increased apoptosis. Mutations in this gene are associated with autosomal recessive coenzyme Q10 deficiency-6 (COQ10D6), which manifests as nephrotic syndrome with sensorineural deafness. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
- Molecular Weight
- 50.7 kDa
- NCBI Accession
- NP_872282
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