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DEFA6 Protein (Myc-DYKDDDDK Tag)

DEFA6 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2719351
  • Target See all DEFA6 Proteins
    DEFA6 (Defensin, alpha 6, Paneth Cell-Specific (DEFA6))
    Protein Type
    Recombinant
    Origin
    • 2
    • 2
    Human
    Source
    • 3
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This DEFA6 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human Defensin alpha 6 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product DEFA6 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    DEFA6 (Defensin, alpha 6, Paneth Cell-Specific (DEFA6))
    Alternative Name
    Defensin alpha 6 (DEFA6 Products)
    Synonyms
    DEFA6 Protein, DEF6 Protein, HD-6 Protein, Defcr6 Protein, defensin alpha 6 Protein, defensin, alpha 6, Paneth cell-specific Protein, defensin, alpha, 6 Protein, DEFA6 Protein, Defa6 Protein
    Background
    Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes appear to be clustered on chromosome 8. The protein encoded by this gene, defensin, alpha 6, is highly expressed in the secretory granules of Paneth cells of the small intestine, and likely plays a role in host defense of human bowel.
    Molecular Weight
    8.9 kDa
    NCBI Accession
    NP_001917
    Pathways
    Cellular Response to Molecule of Bacterial Origin
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