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DMAP1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

DMAP1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2719531
  • Target See all DMAP1 Proteins
    DMAP1 (DNA Methyltransferase 1-Associated Protein 1 (DMAP1))
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 1
    Origin
    • 2
    • 1
    Human
    Source
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This DMAP1 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human DMAP1 (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product DMAP1 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    DMAP1 (DNA Methyltransferase 1-Associated Protein 1 (DMAP1))
    Alternative Name
    Dmap1 (DMAP1 Products)
    Synonyms
    Afu4g07380 Protein, T8I13.5 Protein, DNMAP1 Protein, DNMTAP1 Protein, EAF2 Protein, MEAF2 Protein, SWC4 Protein, zgc:55593 Protein, dnmap1 Protein, dnmtap1 Protein, eaf2 Protein, meaf2 Protein, swc4 Protein, 1500016M21Rik Protein, Dmtap1 Protein, mKIAA1425 Protein, DNA methyltransferase 1-associated protein DMAP1 Protein, DNA methyltransferase 1-associated protein 1 Protein, DNA methyltransferase 1 associated protein 1 Protein, myb-like transcription factor family protein Protein, DNA methyltransferase 1 associated protein 1 L homeolog Protein, AFUA_4G07380 Protein, NFIA_108840 Protein, ACLA_046700 Protein, CpipJ_CPIJ017959 Protein, Bm1_47540 Protein, PMAA_026820 Protein, AFLA_112450 Protein, TSTA_072020 Protein, BDBG_02603 Protein, AT2G47210 Protein, CpipJ_CPIJ007438 Protein, DMAP1 Protein, dmap1 Protein, dmap1.L Protein, Dmap1 Protein
    Background
    This gene encodes a subunit of several, distinct complexes involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication. The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6, among others. Alternatively spliced transcript variants encoding the same protein have been described.
    Molecular Weight
    52.8 kDa
    NCBI Accession
    NP_061973
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