DPPA4 Protein (His tag)

Catalog No. ABIN2719748

Product Details

Target: DPPA4 (Developmental Pluripotency Associated 4 (DPPA4))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This DPPA4 protein is labelled with His tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human DPPA4 (full length, N-term HIS tag) protein expressed in E. coli.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the N-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: DPPA4 (Developmental Pluripotency Associated 4 (DPPA4))

Alternative Name: Dppa4 (DPPA4 Products)

Synonyms: 2410091M23Rik Protein, C76608 Protein, ECAT15-1 Protein, DPPA4 Protein, Dppa4 Protein, developmental pluripotency associated 4 Protein, DppA4 Protein, peptide ABC transporter substrate-binding protein Protein, dipeptide ABC transport system, substrate-binding protein Protein, similar to developmental pluripotency associated 4 isoform 1 Protein, DPPA4 Protein, Dppa4 Protein, dppA4 Protein, HVO_RS14920 Protein, LOC100360556 Protein, LOC683300 Protein

Background: This gene encodes a nuclear factor that is involved in the maintenance of pluripotency in stem cells and essential for embryogenesis. The encoded protein has a scaffold-attachment factor A/B, acinus and PIAS (SAP) domain that binds DNA and is thought to modify chromatin. Mice with a homozygous knockout of the orthologous gene die during late embryonic development or within hours after birth. Knockout embryos are normal in size at embryonic day 18.5 but exhibit skeletal and lung tissue abnormalities. This gene, when mutated, is highly expressed in embryonal carcinomas, pluripotent germ cell tumors, and other cancers and is thought to play an important role in tumor progression. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants.

Molecular Weight: 33.4 kDa

NCBI Accession: NP_060659