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DUOX1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

DUOX1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2719810
  • Target See all DUOX1 Proteins
    DUOX1 (Dual Oxidase 1 (DUOX1))
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 1
    Origin
    Human
    Source
    • 4
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This DUOX1 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human Dual oxidase 1 (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product DUOX1 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    DUOX1 (Dual Oxidase 1 (DUOX1))
    Alternative Name
    Dual Oxidase 1 (DUOX1 Products)
    Synonyms
    Udx1 Protein, duox1 Protein, LNOX1 Protein, NOXEF1 Protein, THOX1 Protein, 9930101G15Rik Protein, AW987690 Protein, Duox2 Protein, LNOX2 Protein, NOXEF2 Protein, P138-TOX Protein, THOX2 Protein, dual oxidase 1 Protein, dual oxidase Protein, duox1 Protein, DUOX1 Protein, duox Protein, LOC5569378 Protein, Duox1 Protein
    Background
    The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes proteins encoded by this gene and the similar DUOX2 gene. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain. This protein generates hydrogen peroxide and thereby plays a role in the activity of thyroid peroxidase, lactoperoxidase, and in lactoperoxidase-mediated antimicrobial defense at mucosal surfaces. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.
    Molecular Weight
    177.1 kDa
    NCBI Accession
    NP_059130
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