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DUSP5 Protein (His tag)

DUSP5 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2719839
  • Target See all DUSP5 Proteins
    DUSP5 (Dual Specificity Phosphatase 5 (DUSP5))
    Protein Type
    Recombinant
    Origin
    • 3
    • 1
    • 1
    Human
    Source
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This DUSP5 protein is labelled with His tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human DUSP5 (full length, N-term HIS tag) protein expressed in E. coli.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product DUSP5 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the N-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    DUSP5 (Dual Specificity Phosphatase 5 (DUSP5))
    Alternative Name
    Dusp5 (DUSP5 Products)
    Synonyms
    DUSP5 Protein, wu:fc03b11 Protein, wu:fc86e02 Protein, MGC84792 Protein, dusp Protein, hvh3 Protein, DUSP Protein, HVH3 Protein, Cpg21 Protein, Gm337 Protein, dual specificity phosphatase 5 Protein, dual specificity phosphatase 5 S homeolog Protein, DUSP5 Protein, dusp5 Protein, dusp5.S Protein, Dusp5 Protein
    Background
    The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, is expressed in a variety of tissues with the highest levels in pancreas and brain, and is localized in the nucleus.
    Molecular Weight
    41.9 kDa
    NCBI Accession
    NP_004410
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