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DYNLT1 Protein (Myc-DYKDDDDK Tag)

DYNLT1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2719883
  • Target See all DYNLT1 Proteins
    DYNLT1 (Dynein, Light Chain, Tctex-Type 1 (DYNLT1))
    Protein Type
    Recombinant
    Origin
    • 1
    • 1
    • 1
    Human
    Source
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This DYNLT1 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human DYNLT1 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product DYNLT1 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    DYNLT1 (Dynein, Light Chain, Tctex-Type 1 (DYNLT1))
    Alternative Name
    Dynlt1 (DYNLT1 Products)
    Synonyms
    cw-1 Protein, tctel1 Protein, dynlt1a Protein, tctex-1 Protein, MGC85297 Protein, tctex1 Protein, Ci-LC3 Protein, CW-1 Protein, TCTEL1 Protein, AGS2 Protein, Tctex1 Protein, dynein light chain Tctex-type 1 L homeolog Protein, dynein light chain Tctex-type 1 Protein, dynein, light chain, Tctex-type 1 Protein, dynlt1.L Protein, DYNLT1 Protein, dynlt1 Protein, Dynlt1 Protein
    Background
    This gene encodes a component of the motor complex, cytoplasmic dynein, which transports cellular cargo along microtubules in the cell. The encoded protein regulates the length of primary cilia which are sensory organelles found on the surface of cells. The protein encoded by this gene interacts with viral proteins, like the minor capsid protein L2 of human papillomavirus, and is required for dynein-mediated delivery of the viral nucleic acid to the host nucleus. This protein interacts with oncogenic nucleoporins to disrupt gene regulation and cause leukemic transformation. Pseudogenes of this gene are present on chromosomes 4 and 17. Alternative splicing results in multiple transcript variants encoding different isoforms.
    Molecular Weight
    12.3 kDa
    NCBI Accession
    NP_006510
    Pathways
    Regulation of G-Protein Coupled Receptor Protein Signaling
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