EDARADD Protein (Transcript Variant B) (Myc-DYKDDDDK Tag)
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- Target See all EDARADD Proteins
- EDARADD (EDAR-Associated Death Domain (EDARADD))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant B
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This EDARADD protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human EDARADD (transcript variant B) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product EDARADD Protein
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EDAR-Associated Death Domain (EDARADD) (AA 1-208) protein (Strep Tag)
Crystallography grade EDARADD Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
EDAR-Associated Death Domain (EDARADD) (AA 1-215) protein (Strep Tag)Crystallography grade EDARADD Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- EDARADD (EDAR-Associated Death Domain (EDARADD))
- Alternative Name
- Edaradd (EDARADD Products)
- Synonyms
- 1810032E07Rik Protein, 5830469M23Rik Protein, A630043P06 Protein, cr Protein, ECTD11A Protein, ECTD11B Protein, ED3 Protein, EDA3 Protein, EDAR (ectodysplasin-A receptor)-associated death domain Protein, EDAR associated death domain Protein, Edaradd Protein, EDARADD Protein
- Background
- This gene was identified by its association with ectodermal dysplasia, a genetic disorder characterized by defective development of hair, teeth, and eccrine sweat glands. The protein encoded by this gene is a death domain-containing protein, and is found to interact with EDAR, a death domain receptor known to be required for the development of hair, teeth and other ectodermal derivatives. This protein and EDAR are coexpressed in epithelial cells during the formation of hair follicles and teeth. Through its interaction with EDAR, this protein acts as an adaptor, and links the receptor to downstream signaling pathways. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
- Molecular Weight
- 23.5 kDa
- NCBI Accession
- NP_542776
- Pathways
- Ubiquitin Proteasome Pathway
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