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FBXO32 Protein (His tag)

FBXO32 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2720649
  • Target See all FBXO32 Proteins
    FBXO32 (F-Box Protein 32 (FBXO32))
    Protein Type
    Recombinant
    Origin
    • 3
    • 2
    • 2
    • 1
    • 1
    Human
    Source
    • 3
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This FBXO32 protein is labelled with His tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human F-box protein 32 (FBXO32), transcript variant 2, full length, with N-terminal HIS tag, expressed in E.Coli, 50 μg (full length, N-term HIS tag, transcript variant 2) protein expressed in E.coli.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product FBXO32 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the N-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    50 mM Tris,8M Urea, pH 8.0.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    FBXO32 (F-Box Protein 32 (FBXO32))
    Abstract
    FBXO32 Products
    Synonyms
    MGC56479 Protein, zgc:56479 Protein, Fbx32 Protein, MAFbx Protein, 4833442G10Rik Protein, AI430017 Protein, ATROGIN1 Protein, Gm20361 Protein, Atrogin1 Protein, F-box protein 32 Protein, fbxo32 Protein, FBXO32 Protein, Fbxo32 Protein
    Background
    This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms.
    Molecular Weight
    24.5 kDa
    NCBI Accession
    NP_680482
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