TNNI2 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2720885

Product Details

Target: TNNI2 (Fast Skeletal Troponin I (TNNI2))

Protein Type: Recombinant

Protein Characteristics: Transcript Variant 2

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This TNNI2 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human Fast skeletal muscle Troponin I (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: TNNI2 (Fast Skeletal Troponin I (TNNI2))

Alternative Name: Fast Skeletal Muscle Troponin I (TNNI2 Products)

Synonyms: AMCD2B Protein, DA2B Protein, FSSV Protein, fsTnI Protein, TnI-F4 Protein, TnI Protein, TNI Protein, hm:zehn0173 Protein, tnni2 Protein, tropI-1d Protein, zgc:86800 Protein, troponin I2, fast skeletal type Protein, troponin I type 2 (skeletal, fast) Protein, troponin I, fast skeletal muscle-like Protein, troponin I, skeletal, fast 2 Protein, troponin I type 2a (skeletal, fast), tandem duplicate 4 Protein, TNNI2 Protein, Tnni2 Protein, tnni2a.4 Protein

Background: This gene encodes a fast-twitch skeletal muscle protein, a member of the troponin I gene family, and a component of the troponin complex including troponin T, troponin C and troponin I subunits. The troponin complex, along with tropomyosin, is responsible for the calcium-dependent regulation of striated muscle contraction. Mouse studies show that this component is also present in vascular smooth muscle and may play a role in regulation of smooth muscle function. In addition to muscle tissues, this protein is found in corneal epithelium, cartilage where it is an inhibitor of angiogenesis to inhibit tumor growth and metastasis, and mammary gland where it functions as a co-activator of estrogen receptor-related receptor alpha. This protein also suppresses tumor growth in human ovarian carcinoma. Mutations in this gene cause myopathy and distal arthrogryposis type 2B. Alternatively spliced transcript variants have been found for this gene.

Molecular Weight: 21.2 kDa

NCBI Accession: NP_001139301