FBXL18 Protein (Myc-DYKDDDDK Tag)
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- Target See all FBXL18 Proteins
- FBXL18 (F-Box and Leucine-Rich Repeat Protein 18 (FBXL18))
- Protein Type
- Recombinant
- Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This FBXL18 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human FBXL18 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product FBXL18 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- FBXL18 (F-Box and Leucine-Rich Repeat Protein 18 (FBXL18))
- Alternative Name
- Fbxl18 (FBXL18 Products)
- Synonyms
- Fbl18 Protein, AI427077 Protein, B130019G13Rik Protein, C330021B20Rik Protein, FBXL18 Protein, zgc:114102 Protein, F-box and leucine rich repeat protein 18 Protein, F-box and leucine-rich repeat protein 18 Protein, FBXL18 Protein, Fbxl18 Protein, fbxl18 Protein
- Background
- The protein encoded by this gene is a member of a family of proteins that contain an approximately 40-amino acid F-box motif. This motif is important for interaction with SKP1 and for targeting some proteins for degradation. The encoded protein has been shown to control the cellular level of FBXL7, a protein that induces mitotic arrest, by targeting it for polyubiquitylation and proteasomal degradation. Members of the F-box protein family, such as FBXL18, are characterized by an approximately 40-amino acid F-box motif. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains.
- Molecular Weight
- 78.7 kDa
- NCBI Accession
- NP_079239
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