FBXO22 Protein (His tag)

Catalog No. ABIN2720948

Product Details

Target: FBXO22 (F-Box Protein 22 (FBXO22))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This FBXO22 protein is labelled with His tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human FBXO22 (full length, N-term HIS tag, transcript variant 1) protein expressed in E. coli.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the N-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: FBXO22 (F-Box Protein 22 (FBXO22))

Alternative Name: Fbxo22 (FBXO22 Products)

Synonyms: FBXO22 Protein, DKFZp469L0535 Protein, fbxo22 Protein, MGC146708 Protein, si:busm1-132m23.3 Protein, FBX22 Protein, FISTC1 Protein, 0610033L19Rik Protein, 1600016C16Rik Protein, F-box protein 22 Protein, FBXO22 Protein, fbxo22 Protein, Fbxo22 Protein

Background: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and, as a transcriptional target of the tumor protein p53, is thought to be involved in degradation of specific proteins in response to p53 induction. Alternative splicing results in multiple transcript variants.

Molecular Weight: 44.5

NCBI Accession: NP_671717

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development