FHL1 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2721133

Product Details

Target: FHL1 (Four and A Half LIM Domains 1 (FHL1))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This FHL1 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human FHL1 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

References

Albrecht, Wick, Hallgren, Tjärnlund, Nagaraju, Andrade, Thompson, Coley, Phadke, Diaz-Gallo, Bottai, Nennesmo, Chemin, Herrath, Johansson, Wikberg, Ytterberg, Zubarev, Danielsson, Krystufkova et al.: "Development of autoantibodies against muscle-specific FHL1 in severe inflammatory myopathies. ..." in: The Journal of clinical investigation, Vol. 125, Issue 12, pp. 4612-24, (2015) (PubMed).

Target Details

Target: FHL1 (Four and A Half LIM Domains 1 (FHL1))

Alternative Name: Fhl1 (FHL1 Products)

Synonyms: fhl1 Protein, MGC89165 Protein, FHL1 Protein, DKFZp468O1927 Protein, fhl Protein, fhla Protein, zgc:92025 Protein, FHL-1 Protein, FHL1A Protein, FHL1B Protein, FLH1A Protein, KYOT Protein, SLIM Protein, SLIM-1 Protein, SLIM1 Protein, SLIMMER Protein, XMPMA Protein, KyoT Protein, Fhl1 Protein, four and a half LIM domains 1 Protein, four and a half LIM domains 1a Protein, Four and a half LIM domains protein 1 Protein, four and a half LIM domains 1 S homeolog Protein, fhl1 Protein, FHL1 Protein, fhl1a Protein, fhl1.S Protein, Fhl1 Protein

Background: This gene encodes a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged, zinc finger domains with four highly conserved cysteines binding a zinc atom in each zinc finger. Expression of these family members occurs in a cell- and tissue-specific mode and these proteins are involved in many cellular processes. Mutations in this gene have been found in patients with Emery-Dreifuss muscular dystrophy. Multiple alternately spliced transcript variants which encode different protein isoforms have been described.[provided by RefSeq, Nov 2009].

Molecular Weight: 31.7 kDa

NCBI Accession: NP_001440